The Amazing Spider-Man swings toward his historic 200th issue! Peter Parker has faced villain after villain over the course of his heroic career, but despite all those victories, one moment will forever torment him - the death of his Uncle Ben. And now, our hero is struck low when not only does Aunt May die, but the man who killed Uncle Ben returns! It's a saga that plumbs the emotional depths of Peter Parker's life like no other. As Spidey struggles through his grief, old villains and new faces emerge: the Kingpin returns and the Black Cat makes her first appearance. Spidey faces Doc Ock in an Annual extravaganza.